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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1659242Generated: November 2, 2026

Hydrogen iodide → 2'-(2-Pyridylmethyl)-p-anisanilide

https://huagongshe.com/reaction/1659242

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen iodideHCID 24841—
Reactant4-Methoxy-2'-[hydroxy(2-pyridyl)methyl]benzanilideHCID 20560042—
Product2'-(2-Pyridylmethyl)-p-anisanilideHCID 20559990—

Reaction Steps

Treatment of 4-methoxy-2'-[hydroxy(2-pyridyl)methyl]benzanilide with hydrogen iodide according to the procedure of Miller, et al., J. Org. Chem., 24, 1364 (1959) provides 2'-(2-pyridylmethyl)-p-anisanilide, m.p. 130.5°-131.5° C. (corr.), from methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE030811
Source datasetuspto-grants-1981_12
ORD IDord-34368341ad3e40debdd8023c1cfa4727
Source noteuspto-grants-1981_12