Methyl iodide → HCID 20559968, compound

HRID 1659258Notes

Reaction equation

HRID 1659258 reaction equation
[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH:17][CH:18]=[O:19])=[N:7][CH:8]=1)[CH3:2].C[I:21].[CH:22](NC1C=CC=CC=1CCC1C=CC=CN=1)=O>CC(C)=O>[I-:21].[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH:17][CH:18]=[O:19])=[N+:7]([CH3:22])[CH:8]=1)[CH3:2]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 20559958HCID 20559958, compoundHCID 20560054HCID 20560054, compound

Product 1

HCID 20559968HCID 20559968, compoundYield 74%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Reaction of 5-ethyl-2-(o-formamidophenethyl)pyridine with methyl iodide in acetone according to the procedure of Example 2 (c) for 2-(o-formamidophenethyl)pyridine provides a 74% yield of analytically pure 5-ethyl-2-(o-formamidophenethyl)-1-methylpyridinium iodide having a melting point of 134.5°-136.5° C.

Sources & evidence

ORD record
ord-0eb591009f7f45c592cfa6f6ad9a0ac8
Source dataset
uspto-grants-1981_12
Patent number
USRE030812

Reaction notes

Loading…