Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)- → 2-(4-Chlorophenyl)-3-methylbutanoyl chloride

Participants

Reaction Steps

10 g of the product of Step D were added to a mixture of 50 ml of petroleum ether (b.p.=35°-70° C.) and 20 ml of thionyl chloride and the mixture was refluxed for 4 hours and was then cooled. The mixture was evaporated to dryness to obtain 10.8 g of D 2-isopropyl-2-p-chlorophenyl acetyl chloride.

Provenance & Evidence