4-Phenyl-N,N-bis(phenylmethyl)-2H-1-benzopyran-2-methanamine → HCID 20560218, compound

Participants

Reaction Steps

2-(N,N-dibenzylaminomethyl)-4-phenyl-3-chromene (2.2 g) was hydrogenated at 651b in -2 in glacial acetic acid in the presence of 5% palladium on carbon (15 mg) until no more hydrogen was taken up. After filtration and removal of solvent in vacuo the residue was treated with ethereal HBr and the resulting solid recrystallised from ethanol/ether to give the title compound as the hydrobromide salt (0.9 g), mp 243°-245° C.

Provenance & Evidence