Benzene, 1-bromo-4-(trifluoromethyl)- → HCID 53763672, compound

HRID 1659311Notes

Reaction equation

HRID 1659311 reaction equation
[CH2:1]([O:3][C:4](=O)[CH2:5][N:6]([CH3:8])[CH3:7])[CH3:2].Br[C:11]1[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][CH:12]=1>>[CH3:7][N:6]([CH2:5][CH:4]1[CH2:14][CH:15]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][CH:12]=2)[C:16]2[C:1](=[CH:2][CH:13]=[CH:12][CH:11]=2)[O:3]1)[CH3:8]

Participants

3

Reactant 2

HCID 67872Benzene, 1-bromo-4-(trifluoromethyl)-HCID 118412Glycine, N,N-dimethyl-, ethyl ester

Product 1

HCID 53763672HCID 53763672, compound

Procedure

The process of example 4 was repeated using N,N-dimethylglycine ethyl ester in place of N,N-dimethylalanine ethyl ester in part (a), and using 4-bromobenzotrifluoride in place of 4-bromochlorobenzene in part (c) to yield the title compound.

Sources & evidence

ORD record
ord-ebecbd4e7f384fec9f96fff61fc9c1b6
Source dataset
uspto-grants-1981_12
Patent number
US04303656

Reaction notes

Loading…