Acetic Anhydride → HCID 13175648, compound

HRID 1659329Notes

Reaction equation

HRID 1659329 reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][N:5]2[C:14]=1[C:13]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N:7]=[CH:6]2.[C:15](OC(=O)C)(=[O:17])[CH3:16]>>[NH:1]([C:2]1[CH:3]=[N:4][N:5]2[C:14]=1[C:13]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N:7]=[CH:6]2)[C:15]([CH3:16])=[O:17]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 13175647HCID 13175647, compound

Product 1

HCID 13175648HCID 13175648, compoundYield 90%

Procedure

19.8 g (0.1 mole) of 1-aminopyrazolo[1,5-c]quinazoline are boiled with 100 ml of acetic anhydride for 1 hour. On cooling the product separates. After filtration, washing and drying, 22.0 g (90%) of 1-acetaminopyrazolo[1,5-c]quinazoline are obtained. M.p.: 256°-258° C.

Workup

  1. temperatureOn cooling the product
  2. filtrationAfter filtration
  3. washwashing
  4. customdrying

Sources & evidence

ORD record
ord-3617076a29044042b651262d807168a2
Source dataset
uspto-grants-1981_12
Patent number
US04303660

Reaction notes

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