HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaldehyde → 1-Nitro-5-methyl-5,6-dihydropyrazolo[1,5-c]quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | 5-(o-Aminophenyl)-4-nitropyrazole | HCID 20560260 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Nitro-5-methyl-5,6-dihydropyrazolo[1,5-c]quinazoline | HCID 135737781 | 92% |
Reaction Steps
20.4 g (0.1 mole) of 5-(o-aminophenyl)-4-nitropyrazole are dissolved in a mixture of 250 ml of water, 400 ml of acetic acid and 175 ml of ethanol, then 10 ml (about 0.1 mole) of acetaldehyde in 10 ml of ethanol are added. Yellow crystals separate, immediately. Thus, 21.0 g (92%) of 1-nitro-5-methyl-5,6-dihydropyrazolo[1,5-c]quinazoline are obtained. M.p.: 173°-175° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04303660 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-125c3022fc9b4dc087b7cae43d92193b |
| Source note | uspto-grants-1981_12 |