Crotonaldehyde → 1-Nitro-5-propenyl-5,6-dihydropyrazolo[1,5-c]quinazoline

HRID 1659338Notes

Reaction equation

HRID 1659338 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[NH:12][N:11]=[CH:10][C:9]=1[N+:13]([O-:15])=[O:14].[CH:16](=O)/[CH:17]=[CH:18]/[CH3:19]>>[N+:13]([C:9]1[CH:10]=[N:11][N:12]2[C:8]=1[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[NH:1][CH:16]2[CH:17]=[CH:18][CH3:19])([O-:15])=[O:14]

Participants

3

Reactant 2

HCID 447466CrotonaldehydeHCID 205602605-(o-Aminophenyl)-4-nitropyrazole

Product 1

HCID 1359707901-Nitro-5-propenyl-5,6-dihydropyrazolo[1,5-c]quinazolineYield 83%

Procedure

5-(o-Aminophenyl)-4-nitropyrazole is reacted with crotonaldehyde as described in Example 11 to give 1-nitro-5-propenyl-5,6-dihydropyrazolo[1,5-c]quinazoline. M.p.: 115°-117° C. Yield: 83%.

Sources & evidence

ORD record
ord-3a19d14bcceb44888c78d53c015e9e30
Source dataset
uspto-grants-1981_12
Patent number
US04303660

Reaction notes

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