Acetic Anhydride → 1-Nitro-5-(p-methoxyphenyl)-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline

HRID 1659344Notes

Reaction equation

HRID 1659344 reaction equation
[N+:1]([C:4]1[CH:5]=[N:6][N:7]2[C:16]=1[C:15]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[NH:9][CH:8]2[C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1)([O-:3])=[O:2].[C:25](OC(=O)C)(=[O:27])[CH3:26]>>[N+:1]([C:4]1[CH:5]=[N:6][N:7]2[C:16]=1[C:15]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:9]([C:25](=[O:27])[CH3:26])[CH:8]2[C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 1357377831-Nitro-5-(p-methoxyphenyl)-5,6-dihydropyrazolo[1,5-c]quinazoline

Product 1

HCID 131756781-Nitro-5-(p-methoxyphenyl)-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazolineYield 99%

Procedure

1-Nitro-5-(p-methoxyphenyl)-5,6-dihydropyrazolo[1,5-c]quinazoline is reacted with acetic anhydride as described in Example 27 to give 1-nitro-5-(p-methoxyphenyl)-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline with a yield of 99%. M.p.: 153°-154° C.

Sources & evidence

ORD record
ord-1b2b47b1717b4dbdbd6950070c54e2bf
Source dataset
uspto-grants-1981_12
Patent number
US04303660

Reaction notes

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