HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 1-Acetamino-5-methyl-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 1-Amino-5-methyl-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline | HCID 13175685 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 1-Acetamino-5-methyl-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline | HCID 13175684 | 90% |
Reaction Steps
20.5 g (0.08 mole) of 1-amino-5-methyl-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline are dissolved in 400 ml of pyridine. 100 ml of acetic anhydride are added and the solution is left to stand at room temperature for 10 hours. A portion of the product separates as a crystalline substance, the remaining portion is separated by evaporating the mother liquor. 21.1 g (90%) of 1-acetamino-5-methyl-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline are obtained. M.p.: 218°-220° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04303660 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-5402d896969143129192155286193ec5 |
| Source note | uspto-grants-1981_12 |