反应详情

27.1 g (0.1 mole) of 1-nitro-5-methyl-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline are hydrogenized in ethanol in the presence of palladium/carbon catalyst. When the reduction is complete, the catalyst is removed by filtration and the filtrate is evaporated in an inert atmosphere under reduced pressure. 20.5 g (81%) of 1-amino-5-methyl-6-acetyl-5,6-dihydropyrazolo[1,5-c]quinazoline are obtained as white crystals. M.p.: 170°-172° C.

1. customthe catalyst is removed by filtration
2. customthe filtrate is evaporated in an inert atmosphere under reduced pressure