Sodium Hydroxide → HCID 20559068, compound

Participants

Reaction Steps

2-Acetamido-1-benzylthio-cyclohexane (74 mg) prepared as above was added to 1 molar aqueous sodium hydroxide solution (30 ml) and refluxed for 19 hours. The reaction mixture was cooled, diluted to 100 ml with water and extracted with diethyl ether (3×50 ml). The ethereal layer was washed with water (25 ml), dried and evaporated to give 2-amino-1-benzylthio-cyclohexane (58 mg). Mass spec. m/e 221 (parent ion), IR 3300 (broad), 1600 and 1500 cm-1.

Provenance & Evidence