HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoeugenol → 4-hydroxy-3-methoxyphenyl-7-methoxy3-methyl-5-(E)-propenylbenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoeugenol | HCID 853433 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-hydroxy-3-methoxyphenyl-7-methoxy3-methyl-5-(E)-propenylbenzofuran | HCID 10314175 | — |
Reaction Steps
150 g ferric chloride in 400 ml water are added to a solution of 100 g (E)-isoeugenol in 1.3 liter 75 percent ethanol and allowed to stand for 24 hours at 0° C. The resulting sediment is filtered off and recrystallized from ethanol, resulting in 53 g trans-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl-7-methoxy3-methyl-5-(E)-propenylbenzofuran ("dehydrodiisoeugenol") as colorless crystals; melting point 132°-133° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04304785 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-1d89cf11714141fd9a7e0bf7dcf364b8 |
| Source note | uspto-grants-1981_12 |