HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-(2-Formamidothiazol-4-yl)-2-ethoxyiminoacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-(2-Amino-4-thiazolyl)-2-ethoxyiminoacetic acid | HCID 53424235 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2-(2-Formamidothiazol-4-yl)-2-ethoxyiminoacetic acid | HCID 54458077 | 87.7% |
Reaction Steps
2-Ethoxyimino-2-(2-aminothiazol-4-yl)acetic acid (syn isomer) (100 g.), formic acid (85.5 g.) and acetic anhydride (190.1 g.) were treated in a similar manner to that of Preparation 24 to give 2-ethoxyimino-2-(2-formamidothiazol-4-yl)acetic acid (syn isomer) (99.1 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04304770 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-b8287c62e23a4936a3a6f5c1614479bf |
| Source note | uspto-grants-1981_12 |