HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-thiopseudourea → HCID 20221228, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-thiopseudourea | HCID 5142 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 5-Aminopentan-1-ol | HCID 75634 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20221228 | HCID 20221228 | — |
Reaction Steps
S-Methylisothiourea is reacted with 5-aminopentanol and sodium hydride in tetrahydrofuran to give O-(5-aminopentyl)isourea, which is reacted with 2-nitroamino-5-(6-methyl-3-pyridylmethyl)-4-pyrimidone in refluxing ethanol to give 2-[5-(O-isoureido)pentylamino]-5-(6-methyl-3-pyridylmethyl)-4-pyrimidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04305945 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-9b7667cd6e9f45afa7f60572cb74ba38 |
| Source note | uspto-grants-1981_12 |