HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminopentan-1-ol → 2-(5-Hydroxypentylamino)-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminopentan-1-ol | HCID 75634 | — |
| Reactant | 5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidone | HCID 12783831 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(5-Hydroxypentylamino)-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone | HCID 20221235 | — |
Reaction Steps
5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino-4-pyrimidone is reacted with 5-aminopentanol in refluxing ethanol to give 2-(5-hydroxypentylamino)-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone which is reacted with cyanamide and hydrogen chloride to give 2-[5-(O-isoureido)pentylamino]-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04305945 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-c724cd8990d5482cb70de0221fd7dedb |
| Source note | uspto-grants-1981_12 |