HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl phosphite → Diethyl (3-ethylisoxazol-5-yl)-methanephosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | 5-(Chloromethyl)-3-ethyl-1,2-oxazole | HCID 12364600 | — |
| Product | Diethyl (3-ethylisoxazol-5-yl)-methanephosphonate | HCID 12520068 | 71.5% |
Reaction Steps
15 g of 5-chloromethyl-3-ethyl-isoxazole and 18 g of triethyl phosphite are slowly heated to 150° C. and kept at this temperature for 21/2 hours. After cooling, the residue is distilled under reduced pressure. 18.2 g of diethyl (3-ethylisoxazol-5-yl)-methanephosphonate, of boiling point 120°-121° C./0.2 mm Hg are obtained. Yield: 71.2%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04305951 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-dd201e48fb17420e90403ba6831e7a52 |
| Source note | uspto-grants-1981_12 |