HuagongsheHuagongshe Chemistry Print Report · For research reference only
Epibromohydrin → 3-Tert.-butyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Epibromohydrin | HCID 18430 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Tert.-butyl-5-(2-hydroxystyryl)-isoxazole | HCID 135973981 | — |
| Product | 3-Tert.-butyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazole | HCID 56628877 | — |
Reaction Steps
This is prepared, using the method described in Example VI, from 3.8 g of 55% strength sodium hydride (0.086 mole), 21 g (0.086 mole) of 3-tert.-butyl-5-(2-hydroxystyryl)-isoxazole and 11.8 g (0.086 mole) of epibromohydrin. 25.0 g (97% of theory) of a colorless oil are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04305951 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-58883e235ca7418fb62512b74e33bf6f |
| Source note | uspto-grants-1981_12 |