HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 6,7-Dichloro-2,3-dihydro-4H-1-benzopyran-4-one oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 6,7-Dichloro-2,3-dihydro-4H-1-benzopyran-4-one | HCID 12664408 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6,7-Dichloro-2,3-dihydro-4H-1-benzopyran-4-one oxime | HCID 85773082 | — |
Reaction Steps
A mixture of 6,7-dichloro-2,3-dihydro-4H-1-benzopyran-4-one (59.7 g), methanol (750 ml), water (75 ml), potassium carbonate (76 g), hydroxylamine HCl (76.4 g) was heated at reflux for 4 hours, then poured into ice-water: the oxime of 6,7-dichloro-2,3-dihydro-4H-1-benzopyran-4-one was filtered off, washed with water, with a small volume of ether, then dried in air. Yield: 62.7 g; m.p. 192°-193°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04305954 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-4e991763a17a4803843d94d2c2b163aa |
| Source note | uspto-grants-1981_12 |