Salicylaldehyde → 3,4-Dihydro-3'-methyl-4-(3-methyl-2-benzothiazolinylidenemethyl)spiro[2H-1-benzopyran-2,2'-benzothiazoline]

HRID 1659909ノート

反応式

HRID 1659909 の反応式
[S:1]([C:5]1[CH:11]=[CH:10][C:8](C)=[CH:7][CH:6]=1)([O-])(=O)=O.[CH3:12][C:13]1[S:14][C:15]2[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=2[N+:17]=1[CH3:18].[CH:23]1[CH:28]=[C:27]([CH:29]=O)[C:26]([OH:31])=[CH:25][CH:24]=1.[NH:32]1[CH2:37]CC[CH2:34][CH2:33]1>C(O)C>[CH3:18][N:17]1[C:16]2[CH:19]=[CH:20][CH:21]=[CH:22][C:15]=2[S:14][C:13]21[CH2:12][CH:29]([CH:34]=[C:33]1[N:32]([CH3:37])[C:11]3[CH:10]=[CH:8][CH:7]=[CH:6][C:5]=3[S:1]1)[C:27]1[CH:28]=[CH:23][CH:24]=[CH:25][C:26]=1[O:31]2

参加物

5

反応物 3

HCID 6998SalicylaldehydeHCID 8082PiperidineHCID 102307Benzothiazolium, 2,3-dimethyl-, 4-methylbenzenesulfonate (1:1)

生成物 1

HCID 543852913,4-Dihydro-3'-methyl-4-(3-methyl-2-benzothiazolinylidenemethyl)spiro[2H-1-benzopyran-2,2'-benzothiazoline]

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

40.2 g of 2,3-dimethylbenzothiazolium tosylate and 7.32 g of salicylic aldehyde were mixed in 1200 ml of ethanol; to this mixture were added 12 ml of piperidine with stirring. Stirring was continued for 1 hour at room temperature. A precipitate was formed which was filtered out and washed with ethanol.

後処理

  1. stirringStirring
  2. customA precipitate was formed which
  3. filtrationwas filtered out
  4. washwashed with ethanol

出典と根拠

ORDレコード
ord-d96a7052256b4491968160022c1a4b1a
出典データセット
uspto-grants-1981_12
特許番号
US04306017

反応ノート

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