HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron trifluoride etherate → Ethyl 3-(4-aminophenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-(4-Aminophenyl)propionic acid | HCID 75451 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 3-(4-aminophenyl)propanoate | HCID 10442595 | — |
Reaction Steps
A solution of 10.0 g. 4-aminohydrocinnamic acid in 100 ml. of absolute ethanol containing 16 ml. of boron trifluoride etherate is heated to reflux for 48 hours. The solution is then cooled, poured into 5% aqueous sodium carbonate, and extracted with methylene chloride. Evaporation of the organic extracts yields ethyl 4-aminohydrocinnamate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04305959 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-1062454d76754c24a240e9b08d291193 |
| Source note | uspto-grants-1981_12 |