HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1659987Generated: October 25, 2026
Acetic Acid → 7-Mercapto-1,4-benzodioxane-5-carboxylic acid
https://huagongshe.com/reaction/1659987
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tin atom | HCID 5352426 | — |
| Reactant | 7-(Chlorosulphonyl)-2,3-dihydro-1,4-benzodioxin-5-carboxylic acid | HCID 6455316 | — |
| Solvent | Water | HCID 962 | — |
| Product | 7-Mercapto-1,4-benzodioxane-5-carboxylic acid | HCID 20544694 | 90% |
Reaction Steps
243 g of 7-chlorosulfonyl-1,4-benzodioxane-5-carboxylic acid and 654 cm3 of acetic acid were introduced into a balloon flask provided with an agitator and a condenser. The mixture was heated to 90° C. and then cooled to 45° C. 389 g of tin and 1,744 cm3 of hydrochloric acid were then added. The mixture was heated to 55°-60° C., cooled and poured into water. The precipitate was dried off, washed and dried. 166 g of 7-mercapto-1,4-benzodioxane-5-carboxylic acid were obtained (M.P.: 191°-192° C.; yield: 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04306072 |
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| Source dataset | uspto-grants-1981_12 |
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| ORD ID | ord-dd89d8c58d684eb7bac91bf46f75dd54 |
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| Source note | uspto-grants-1981_12 |
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