Thionyl Chloride → HCID 20544705, compound

HRID 1659992Notes

Reaction equation

HRID 1659992 reaction equation
S(Cl)([Cl:3])=O.[CH3:5][N:6]([CH3:23])[S:7]([C:10]1[CH:11]=[C:12]([C:20](O)=[O:21])[C:13]2[O:18][CH2:17][CH2:16][O:15][C:14]=2[CH:19]=1)(=[O:9])=[O:8]>>[CH3:5][N:6]([CH3:23])[S:7]([C:10]1[CH:11]=[C:12]([C:20]([Cl:3])=[O:21])[C:13]2[O:18][CH2:17][CH2:16][O:15][C:14]=2[CH:19]=1)(=[O:9])=[O:8]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 64553187-(N,N-dimethylsulphamoyl)-2,3-dihydro-1,4-benzodioxin-5-carboxylic acid

Product 1

HCID 20544705HCID 20544705, compoundYield 100.1%

Procedure

190 g of thionyl chloride and 153 g of 7-dimethylsulfamoyl-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated and then the excess thionyl chloride was distilled off. 163 g of 7-dimethylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 160°-162° C.; yield: 100%).

Workup

  1. customprovided with a condenser
  2. temperatureThe mixture was heated
  3. distillationthe excess thionyl chloride was distilled off

Sources & evidence

ORD record
ord-65b3f9d4c83d46e3b509c4dc36ff652e
Source dataset
uspto-grants-1981_12
Patent number
US04306072

Reaction notes

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