Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 6,7-Dibromo-8-nitro-1,4-benzodioxane-5-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 6,7-Dibromo-8-nitro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic acid | HCID 20544759 | — |
| 생성물 | 6,7-Dibromo-8-nitro-1,4-benzodioxane-5-carbonyl chloride | HCID 20544755 | 91% |
반응 단계
96 g of 6,7-dibromo-8-nitro-1,4-benzodioxane-5-carboxylic acid and 200 ml of thionyl chloride were introduced into a balloon flask provided with an agitator and a thermometer. The mixture was heated under reflux and then the excess thionyl chloride was removed under vacuum. The residue was dissolved in 100 ml of isopropyl ether and then the solvent removed and the product air-dried. 91 g of 6,7-dibromo-8-nitro-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 215° C.; yield: 91%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04306072 |
| 출처 데이터셋 | uspto-grants-1981_12 |
| ORD ID | ord-e49f903ead5e436f9a73e06cbee9ba4a |
| 출처 메모 | uspto-grants-1981_12 |