2-Aminomethyl-1-ethylpyrrolidine → HCID 70549576, compound

HRID 1660043Notes

Reaction equation

HRID 1660043 reaction equation
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[C:10]([C:11]([Cl:13])=[O:12])[C:5]=2[O:4][CH2:3][CH2:2]1.[CH2:14]([N:16]1[CH2:20][CH2:19][CH2:18][CH:17]1[CH2:21][NH2:22])[CH3:15]>>[ClH:13].[CH2:14]([N:16]1[CH2:20][CH2:19][CH2:18][CH:17]1[CH2:21][NH:22][C:11]([C:10]1[C:5]2[O:4][CH2:3][CH2:2][O:1][C:6]=2[CH:7]=[CH:8][CH:9]=1)=[O:12])[CH3:15]

Participants

3

Reactant 2

HCID 1172952-Aminomethyl-1-ethylpyrrolidineHCID 27950312,3-Dihydro-1,4-benzodioxine-5-carbonyl chloride

Product 1

HCID 70549576HCID 70549576, compound

Procedure

In the same manner as described in Example 17, by reaction of 1,4-benzodioxane-5-carbonyl chloride with the 1-ethyl-2-aminomethyl pyrrolidine, the N-(1-ethyl-2-pyrrolidylmethyl)-1,4-benzodioxane-5-carboxamide hydrochloride was obtained (M.P.: 149°-150° C.).

Sources & evidence

ORD record
ord-8509b1b0ff764aa3a9e88d49c53e75f6
Source dataset
uspto-grants-1981_12
Patent number
US04306072

Reaction notes

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