Bromine → 2-Bromo-5-(2-methyloctan-2-YL)phenol

HRID 1660075Notes

Reaction equation

HRID 1660075 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:16])([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH3:9])[CH:5]=[CH:6][CH:7]=1.[Br:17]Br>C(Cl)(Cl)(Cl)Cl>[Br:17][C:7]1[CH:6]=[CH:5][C:4]([C:8]([CH3:16])([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH3:9])=[CH:3][C:2]=1[OH:1]

Participants

4

Reactant 2

HCID 24408BromineHCID 127881863-(2-Methyloctan-2-yl)phenol

Product 1

HCID 127881872-Bromo-5-(2-methyloctan-2-YL)phenol

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent2×

Procedure

To a 0° C. solution of 110 g. (0.50 mole) of 2-(3-hydroxyphenyl)-2-methyloctane in 200 ml. of carbon tetrachloride was added dropwise a solution of 80 g. (0.50 mole) of bromine in 90 ml. of carbon tetrachloride (reaction temperature ≤30° C. with cooling). The reaction mixture was stirred an additional 15 minutes and was then evaporated to yield 150 g. (100%) of product as an oil.

Workup

  1. customTo a 0° C.
  2. customwas then evaporated
  3. customto yield 150 g

Sources & evidence

ORD record
ord-fbfeedec4ef64ed294ab0ea710e81dc3
Source dataset
uspto-grants-1981_12
Patent number
US04306097

Reaction notes

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