反应详情

A mixture of 50 ml. of acetic anhydride and 0.1 ml. of conc. sulfuric acid was stirred at room temperature for 5 minutes. To this mixture was added 15 g. (0.025 mole) of 5-amino-2,4,6-triiodoisophthaloyl chloride in one portion and stirring was continued at room temperature for one hour. The mixture was stored overnight at 0°. Filtration furnished 16 g. of solid material. The product was recrystallized from ethyl acetate to furnish 10 g. (63%) of pure product. The compound was shown to be pure by tlc (silica plate-benzene/acetone 80/20).

1. additionA mixture of 50 ml
2. additionTo this mixture was added 15 g
3. waitThe mixture was stored overnight at 0°
4. filtrationFiltration
5. customfurnished 16 g
6. customThe product was recrystallized from ethyl acetate
7. customto furnish 10 g