1-Bromo-2-Chloroethane → HCID 20557540, compound

HRID 1660130Notes

Reaction equation

HRID 1660130 reaction equation
[O:1]=[C:2]1[N:6]2[CH2:7][CH2:8][CH2:9][CH:10]([C:11]([O:13][CH3:14])=[O:12])[N:5]2[C:4](=[O:15])[NH:3]1.Br[CH2:17][CH2:18][Cl:19]>>[Cl:19][CH2:18][CH2:17][N:3]1[C:2](=[O:1])[N:6]2[CH2:7][CH2:8][CH2:9][CH:10]([C:11]([O:13][CH3:14])=[O:12])[N:5]2[C:4]1=[O:15]

Participants

3

Reactant 2

HCID 78491-Bromo-2-ChloroethaneHCID 20557501HCID 20557501, compound

Product 1

HCID 20557540HCID 20557540, compound

Procedure

Alkylation of methyl hexahydro-1,3-dioxo-1H-1,2,4-triazolo[1,2-a]pyridazine-5-carboxylate with 1-bromo-2-chloroethane in a manner analogous to that described in the preceding paragraph gave methyl 2-(2-chloroethyl)-2,3,5,6,7,8-hexahydro-1,3-dioxo-1H-1,2,4-triazolo[1,2-a]pyridazine-5-carboxylate of melting point 94°-95° C.

Sources & evidence

ORD record
ord-937e36f1ec8b420890800cceb1476581
Source dataset
uspto-grants-1981_12
Patent number
US04307094

Reaction notes

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