HCID 20557499, compound → HCID 20557558, compound

HRID 1660141Notes

Reaction equation

HRID 1660141 reaction equation
C([S:4][CH2:5][N:6]1[C:18](=[O:19])[N:9]2[CH2:10][CH2:11][CH2:12][CH:13]([C:14]([O:16]C)=[O:15])[N:8]2[C:7]1=[O:20])(=O)C>C(OCC)(=O)C.CCCCCC>[SH:4][CH2:5][N:6]1[C:18](=[O:19])[N:9]2[CH2:10][CH2:11][CH2:12][CH:13]([C:14]([OH:16])=[O:15])[N:8]2[C:7]1=[O:20]

Participants

3

Reactant 1

HCID 20557499HCID 20557499, compound

Product 1

HCID 20557558HCID 20557558, compoundYield 29%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

In a manner analogous to that described in Example 32, from methyl 2-acetylthiomethyl-2,3,5,6,7,8-hexahydro-1,3-dioxo-1H-1,2,4-triazolo[1,2-a]pyridazine-5-carboxylate there was obtained in 29% yield 2,3,5,6,7,8-hexahydro-2-mercaptomethyl-1,3-dioxo-1H-1,2,4-triazolo[1,2-a]pyridazine-5-carboxylic acid of melting point 157.5°-158.5° C. (from ethyl acetate/hexane).

Sources & evidence

ORD record
ord-0c1e6de59d8444688fa28c1aaa72dc15
Source dataset
uspto-grants-1981_12
Patent number
US04307094

Reaction notes

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