(+-)-alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol → HCID 131712623, compound

HRID 1660151Notes

Reaction equation

HRID 1660151 reaction equation
[Br:1][C:2]1[S:6][C:5]([CH3:7])=[N:4][C:3]=1[CH2:8][Cl:9].[Cl:10][C:11]1[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:12]=1[CH:18]([OH:25])[CH2:19][N:20]1[CH:24]=[CH:23][N:22]=[CH:21]1>C(O)C>[ClH:9].[Br:1][C:2]1[S:6][C:5]([CH3:7])=[N:4][C:3]=1[CH2:8][O:25][CH:18]([C:12]1[CH:13]=[CH:14][C:15]([Cl:17])=[CH:16][C:11]=1[Cl:10])[CH2:19][N:20]1[CH:24]=[CH:23][N:22]=[CH:21]1

Participants

4

Reactant 2

HCID 32238(+-)-alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanolHCID 12790770HCID 12790770, compound

Product 1

HCID 131712623HCID 131712623, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following the procedure of Example 1b, reaction of 5-bromo-4-chloromethyl-2-methylthiazole and 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol, yields the title compound, m.p. 247°-248° C. (absolute ethanol).

Sources & evidence

ORD record
ord-69aed406162048318b148ecfe85ba52f
Source dataset
uspto-grants-1981_12
Patent number
US04307105

Reaction notes

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