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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1660191Generated: October 29, 2026

Hydrogen Bromide → 1,4-Dimethyl-2-[(2-aminoethyl)thiomethyl]imidazole dihydrobromide

https://huagongshe.com/reaction/1660191

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantCysteamine HydrochlorideHCID 9082—
Reactant(1,4-dimethyl-1H-imidazol-2-yl)methanolHCID 12923402—
ReactantIsopropanol methanolHCID 21255859—
Product1,4-Dimethyl-2-[(2-aminoethyl)thiomethyl]imidazole dihydrobromideHCID 20557969—

Reaction Steps

The reaction of 1,4-dimethyl-2-hydroxymethylimidazole (2.5 g.) with cysteamine hydrochloride (2.5 g.) in aqueous hydrobromic acid by the method described in Example 1 (i) (a) gave 1,4-dimethyl-2-[(2-aminoethyl)thiomethyl]imidazole dihydrobromide (6.2 g.), m.p. 161°-163° (from isopropyl alcohol-methanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04307101
Source datasetuspto-grants-1981_12
ORD IDord-ec79349685d94b25a127227e7a6db9d8
Source noteuspto-grants-1981_12