HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diboron → (3-Chloro-5-methylpyrazin-2-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diboron | HCID 6328200 | — |
| Reactant | 3-Chloro-5-methylpyrazine-2-carboxylic acid | HCID 20557998 | — |
| Product | (3-Chloro-5-methylpyrazin-2-yl)methanol | HCID 20557611 | — |
Reaction Steps
Reduction of 3-chloro-5-methyl-2-pyrazinecarboxylic acid (prepared by alkaline hydrolysis of the methyl ester) with diborane gives 3-chloro-2-hydroxymethyl-5-methylpyrazine which, using the above procedure, yields N-methyl-N'-[2-((3-chloro-5-methyl-2-pyrazinyl)methylthio)ethyl]thiourea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04307101 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-e6330514f4ab495aae57cf022376567d |
| Source note | uspto-grants-1981_12 |