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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1660246Generated: November 1, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-(3-isoxazolylmethylthio)ethyl]thiourea

https://huagongshe.com/reaction/1660246

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant2-((Isoxazol-3-ylmethyl)thio)ethanamineHCID 12923417—
ProductN-benzoyl-N'-[2-(3-isoxazolylmethylthio)ethyl]thioureaHCID 20557750—

Reaction Steps

3-[(2-Aminoethyl)thiomethyl]isoxazole is reacted with benzoyl isothiocyanate by the procedure of Example 18 to give N-benzoyl-N'-[2-(3-isoxazolylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(3-isoxazolylmethylthio)ethyl]thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04307101
Source datasetuspto-grants-1981_12
ORD IDord-12ac04b63a9e45248c442a04b528df6e
Source noteuspto-grants-1981_12