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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1660253Generated: October 31, 2026

(2-Isothiocyanatoethyl)dimethylamine → N-(2-dimethylaminoethyl)-N'-[2-(3-isothiazolylmethylamino)ethyl]thiourea

https://huagongshe.com/reaction/1660253

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Isothiocyanatoethyl)dimethylamineHCID 3853726—
ReactantN-(3-isothiazolylmethyl)ethylenediamineHCID 20557777—
ProductN-(2-dimethylaminoethyl)-N'-[2-(3-isothiazolylmethylamino)ethyl]thioureaHCID 20557944—

Reaction Steps

By the procedure of Example 40(a)(ii), N-(3-isothiazolylmethyl)ethylenediamine is reacted with 2-dimethylaminoethyl isothiocyanate to give N-(2-dimethylaminoethyl)-N'-[2-(3-isothiazolylmethylamino)ethyl]thiourea. Reacting with hydrobromic acid gives the hydrobromide salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04307101
Source datasetuspto-grants-1981_12
ORD IDord-7f681024058f4651939dcb708a755331
Source noteuspto-grants-1981_12