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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1660262Generated: October 31, 2026

Ethylenediamine → N-(2-Dimethylaminoethyl)-N'-[2-(2-benzimidazolylmethylamino)-ethyl]thiourea

https://huagongshe.com/reaction/1660262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant2-ChloromethylbenzimidazoleHCID 78571—
Reactant(2-Isothiocyanatoethyl)dimethylamineHCID 3853726—
ReactantN1-((1H-Benzo[d]imidazol-2-yl)methyl)ethane-1,2-diamineHCID 15365342—
ProductN-(2-Dimethylaminoethyl)-N'-[2-(2-benzimidazolylmethylamino)-ethyl]thioureaHCID 54373380—

Reaction Steps

N-(2-Benzimidazolylmethyl)ethylenediamine, prepared by reacting ethylenediamine with 2-chloromethylbenzimidazole by the procedure of Example 40, is reacted with 2-dimethylaminoethyl isothiocyanate by the procedure of Example 40 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04307101
Source datasetuspto-grants-1981_12
ORD IDord-10977a8dfaef4297a54696a5570126a8
Source noteuspto-grants-1981_12