1-Methylpyrrole → HCID 20523553, compound

HRID 1660295Notes

Reaction equation

HRID 1660295 reaction equation
[Cl:1][C:2]1[C:3]([Cl:15])=[C:4]([Cl:14])[C:5]([Cl:13])=[C:6]2[C:11](=[O:12])[O:10][C:8](=[O:9])[C:7]=12.[CH3:16][N:17]1[CH:21]=[CH:20][CH:19]=[CH:18]1.[Cl-].[Al+3].[Cl-].[Cl-]>ClC1C=CC=CC=1>[CH3:16][N:17]1[CH:21]=[CH:20][CH:19]=[C:18]1[C:11]([C:6]1[C:5]([Cl:13])=[C:4]([Cl:14])[C:3]([Cl:15])=[C:2]([Cl:1])[C:7]=1[C:8]([OH:10])=[O:9])=[O:12].[C:16]1([N:17]2[CH:21]=[CH:20][CH:19]=[C:18]2[C:8]([C:7]2[CH:2]=[CH:3][CH:4]=[CH:5][C:6]=2[C:11]([OH:10])=[O:12])=[O:9])[CH:4]=[CH:3][CH:2]=[CH:7][CH:6]=1

Participants

6

Reactant 3

HCID 73041-MethylpyrroleHCID 8326Tetrachlorophthalic anhydrideHCID 6451240Aluminum(III) Chloride

Product 2

HCID 20523553HCID 20523553, compoundHCID 20523556HCID 20523556, compound

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Procedure

Proceeding in a similar fashion to the one described in part A of Example 17, 28.6 g (0.01 mole) of tetrachlorophthalic anhydride, 16.2 g (0.2 mole) of N-methylpyrrole and 40 g (0.3 mole) of aluminum chloride were interacted in 50 ml of dry chlorobenzene to obtain 2-[(1-methyl-2-pyrrolyl)carbonyl]-3,4,5,6-tetrachlorobenzoic acid (Formula IX: Ro =R1 =R2 =R3 =Cl; R7 =CH3) having a melting point of 203°-205° C.

Sources & evidence

ORD record
ord-80d63382f9ac4560ac5b3d467af1b110
Source dataset
uspto-grants-1981_12
Patent number
US04307018

Reaction notes

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