HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-chloro-4-fluoro- → 1-(4-Chlorophenyl)-2-ethyl-1'-methylspiro[indoline-3,4'-piperidine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-chloro-4-fluoro- | HCID 9604 | — |
| Reactant | 2-Ethyl-1'-methylspiro[indoline-3,4'-piperidine] | HCID 12801643 | — |
| Product | 1-(4-Chlorophenyl)-2-ethyl-1'-methylspiro[indoline-3,4'-piperidine] | HCID 20442637 | — |
Reaction Steps
By following the procedure of Example 1c, 2-ethyl-1'-methylspiro[indoline-3,4'-piperidine], the free base of part a, is treated with 4-chlorofluorobenzene to yield 1-(4-chlorophenyl)-2-ethyl-1'-methylspiro[indoline-3,4'-piperidine].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04307235 |
| Source dataset | uspto-grants-1981_12 |
| ORD ID | ord-a7440c80a1bb447e89e390fa84d7d920 |
| Source note | uspto-grants-1981_12 |