関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | Methyl 2-acetamidoethyldithiocarbamate | HCID 20501582 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4-(2-Acetamidoethyl)-thiosemicarbazide | HCID 20501583 | — |
反応手順
A solution of methyl N-(2-acetamidoethyl)-dithiocarbamate (57.7 g) and hydrazine hydrate (14.6 cc) in absolute ethanol (300 cc) is heated under reflux for 2 hours. The mixture is then cooled to 4° C. and is filtered, and the insoluble matter is dried at 30° C. under 0.05 mm Hg. 4-(2-Acetamidoethyl)-thiosemicarbazide (39.5 g) is obtained in the form of white crystals (instantaneous m.p. [Kofler]=171° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04307230 |
|---|
| 出典データセット | uspto-grants-1981_12 |
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| ORD ID | ord-db5ec13e60d24d3f9d445a9b02bf6e4c |
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| 出典メモ | uspto-grants-1981_12 |
|---|
