Methanol → 5-Amino-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)isoquinolin-1(2H)-one
Reaction equation
[CH3:28][OH:29].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:9][n:10]2[c:11](=[O:23])[c:12]3[cH:13][cH:14][cH:15][c:16]([N+:20]([O-:21])=[O:22])[c:17]3[cH:18][cH:19]2)[cH:7][n:8]1)([F:24])[F:25].[H:26][H:27]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH2:9][n:10]2[c:11](=[O:23])[c:12]3[cH:13][cH:14][cH:15][c:16]([NH2:20])[c:17]3[cH:18][cH:19]2)[cH:7][n:8]1)([F:24])[F:25]Participants
4
Sources & evidence
- ORD record
- ord-a7143e4a9b0c496ca362fb4b6cdadaf2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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