HCID 10877513, compound → HCID 20556793, compound

HRID 1660508Notes

Reaction equation

HRID 1660508 reaction equation
[C:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([Cl:14])=[O:13])=[CH:7][C:6]=1[O:15][CH3:16])(=[O:3])[CH3:2].[S:17](=[O:20])(=[O:19])=[O:18].O1CCOCC1>ClCCl>[C:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]([S:17]([OH:20])(=[O:19])=[O:18])[C:12]([Cl:14])=[O:13])=[CH:7][C:6]=1[O:15][CH3:16])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 10877513HCID 10877513, compoundHCID 157345454-Acetoxy-3-methoxyphenylacetyl chloride

Product 1

HCID 20556793HCID 20556793, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 4-acetoxy-3-methoxyphenylacetyl chloride (2.42 g, 10 mmole) in dichloromethane (20 ml) was treated with a suspension of sulphur trioxide - dioxane complex (15 mmole) dichloroethane at 0° C. This mixture was stirred at room temperature for eighteen hours and evaporated to afford a yellow gum. νmax. (CHCL3) 1800, 1748 cm-1.

Workup

  1. customevaporated
  2. customto afford a yellow gum

Sources & evidence

ORD record
ord-3fe4e8d83c874ba6bfaba783b339a44b
Source dataset
uspto-grants-1981_12
Patent number
US04308259

Reaction notes

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