反应详情

温度

5 °C

Cyclohexanecarboxylic acid (2,2,2-trichloroethylidene)hydrazide was prepared by refluxing a solution containing 23.0 grams (0.162 mol) of cyclohexanecarboxylic acid hydrazide and 44.2 grams (0.3 mol) of trichloroacetaldehyde in 300 ml milliliters of benzene. Water was removed as formed. After 3 hours, the reaction mixture was concentrated to a volume of 100 milliliters, diluted with 500 milliliters of hexane, chilled to 5° C., and filtered to yield 34 grams of the desired hydrazide as a white solid, melting point 178°-180° C.

1. temperatureby refluxing a solution
2. customWater was removed
3. customas formed
4. concentrationthe reaction mixture was concentrated to a volume of 100 milliliters
5. additiondiluted with 500 milliliters of hexane
6. filtrationfiltered