Acetic Acid → HCID 25056269, compound

Participants

Reaction Steps

500 mg of the compound obtained in Example 11 was dissolved in 3 mL of ethyl acetate to which a solution of 74.5 mg of acetic acid in 1 mL of ethyl acetate was then slowly added followed by stirring for 30 min. The reaction mixture was concentrated, to which 2 mL of ethyl acetate and 1 mL of 2-propanol were then added followed by stirring. 15 mL of hexane was added thereto, and the resulting mixture was stirred for 10 min and filtered to afford 495 mg of the title compound as a solid.

Provenance & Evidence