L-Malic Acid → HCID 25056527, compound

Participants

Reaction Steps

498 mg of the compound obtained in Example 11 was dissolved in 4 mL of acetone to which a solution of 166 mg of L-malic acid in 1 mL of acetone was then slowly added followed by stirring for 30 min. The reaction mixture was concentrated, to which 2 mL of ethyl acetate and 1 mL of 2-propanol were then added followed by stirring. 15 mL of hexane was added thereto, and the resulting mixture was stirred for 10 min and filtered to afford 506 mg of the title compound as a solid.

Provenance & Evidence