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HRID1660786

反应详情

EQUATION

反应方程式

HRID 1660786 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)c1ccc(N)cn1
HCID13816714

Ethyl 5-aminopyridine-2-carboxylate

C8H10N2O2

结构：COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)nc3)cc21
HCID24762394

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(Cl)ccc2OC)CCO3)cn1
HCID66789232

未命名化合物

PROCEDURE

实验过程

5-{[4-(5-Chloro-2-methoxy-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl]-amino}-pyridine-2-carboxylic acid, MS (ISP): m/e=502.0, 503.9 (M−H), was prepared as described in example 1, steps 1 to 6. Step 5 was performed using 5-amino-pyridine-2-carboxylic acid ethyl ester and yielded 5-{[4-(5-chloro-2-methoxy-benzenesulfonyl)-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl]-amino}-pyridine-2-carboxylic acid ethyl ester, which was hydrolyzed in step 6.