反应详情

A suspension of N,N,N′-trimethyl-N′-(4-nitro-2-trifluoromethyl-phenyl)-propane-1,3-diamine (1 g, 3.28 mmol) and Raney Ni (˜0.300 g) in MeOH (20 mL) is stirred for 2 h 40 min at rt, under a hydrogen atmosphere. The reaction mixture is filtered through a pad of Celite and concentrated to afford the title compound as a brown oil: ES-MS: 276.2 [M+H]+; single peak at tR=1.30 min (System 1).

1. filtrationThe reaction mixture is filtered through a pad of Celite
2. concentrationconcentrated