HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → [4-(3-Amino-pyridin-2-ylamino)-2-chloro-phenyl]-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | [2-Chloro-4-(3-nitropyridin-2-ylamino)-phenyl]-acetic acid ethyl ester | HCID 67023632 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | [4-(3-Amino-pyridin-2-ylamino)-2-chloro-phenyl]-acetic acid ethyl ester | HCID 67021554 | — |
Reaction Steps
The title compound is prepared as described in Step 7.3 but using [2-chloro-4-(3-nitropyridin-2-ylamino)-phenyl]-acetic acid ethyl ester and EtOH as the solvent. The reaction mixture is stirred for 22 h at rt. Title compound: ES-MS: 306.1 [M+H]+; single peak at tR=3.06 min (System 1); Rf=0.16 (Hexane/EtOAc, 1:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-b84c3251b034437d85d37aeff8b00422 |
| Source note | uspto-grants-2011_10 |