HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline → HCID 11993677, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline | HCID 59134564 | — |
| Reactant | (2-Chloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid | HCID 67021590 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 11993677 | HCID 11993677 | — |
Reaction Steps
The title compound is prepared as described in Example 1 but using (2-chloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid (Step 16.1) and 4-(4-ethyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenylamine (see WO 03/099771). Title compound: ES-MS: 556.9 [M+H]+; single peak at tR=3.36 min (System 1); Rf=0.13 (CH2Cl2/MeOH+1% NH33aq, 9:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-75f62f30409e4773a5b660ff2523e016 |
| Source note | uspto-grants-2011_10 |