HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenylboronic acid → HCID 67021352, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Reactant | 3-Bromo-5-(trifluoromethyl)aniline | HCID 2735880 | — |
| Product | HCID 67021352 | HCID 67021352 | — |
Reaction Steps
The title compound is prepared as described in Example 13 but using 5-amino-3-bromobenzotrifluoride (OAKWOOD PRODUCTS; Inc.) and 1.5 equiv of 4-cyanophenylboronic acid (MATRIX SCIENTIFIC). Silica gel column chromatography purification (Hexane/EtOAc, 4:1) provides the title compound as a white solid: ES-MS: 262.0 [M-H]−; single peak at tR=4.37 min (System 1); Rf=0.09 (Hexane/EtOAc, 4:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030311B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-6174a44d17e04db68e49385936773f7f |
| Source note | uspto-grants-2011_10 |