HCID 67021267, compound → {4-[5-(4-Methoxyphenyl)-benzoimidazol-1-yl]-phenyl}-acetic acid

HRID 1660971Notes

Reaction equation

HRID 1660971 reaction equation
C([O:3][C:4](=[O:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[C:16]3[CH:17]=[CH:18][C:19]([C:21]4[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=4)=[CH:20][C:15]=3[N:14]=[CH:13]2)=[CH:8][CH:7]=1)C>C(Cl)Cl.CO>[CH3:28][O:27][C:24]1[CH:23]=[CH:22][C:21]([C:19]2[CH:18]=[CH:17][C:16]3[N:12]([C:9]4[CH:10]=[CH:11][C:6]([CH2:5][C:4]([OH:29])=[O:3])=[CH:7][CH:8]=4)[CH:13]=[N:14][C:15]=3[CH:20]=2)=[CH:26][CH:25]=1

Participants

3

Reactant 1

HCID 67021267HCID 67021267, compound

Product 1

HCID 67021579{4-[5-(4-Methoxyphenyl)-benzoimidazol-1-yl]-phenyl}-acetic acid

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

The title compound is prepared as described in Step 20.1 (Procedure B) but using {4-[5-(4-methoxy-phenyl)-benzoimidazol-1-yl]-phenyl}-acetic acid ethyl ester. The title compound: ES-MS: 359.3 [M+H]+; single peak at tR=3.60 min (System 1); Rf=0.26 (CH2Cl2/MeOH+1% NH3aq, 9:1).

Workup

  1. customThe title compound is prepared

Sources & evidence

ORD record
ord-b3fbafd20d5241c4a4362074757d50e6
Source dataset
uspto-grants-2011_10
Patent number
US08030311B2

Reaction notes

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