3-Cyclopropyl-1-phenyl-1H-pyrazol-5-amine → HCID 67021632, compound

HRID 1661000Notes

Reaction equation

HRID 1661000 reaction equation
[N:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[N:3]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][C:17]([OH:19])=O)=[CH:12][CH:11]=2)[CH:2]=1.[CH:20]1([C:23]2[CH:24]=[C:25]([NH2:34])[N:26]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[N:27]=2)[CH2:22][CH2:21]1>>[CH:20]1([C:23]2[CH:24]=[C:25]([NH:34][C:17](=[O:19])[CH2:16][C:13]3[CH:12]=[CH:11][C:10]([N:3]4[C:4]5=[N:5][CH:6]=[CH:7][CH:8]=[C:9]5[N:1]=[CH:2]4)=[CH:15][CH:14]=3)[N:26]([C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=3)[N:27]=2)[CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 27580103-Cyclopropyl-1-phenyl-1H-pyrazol-5-amineHCID 53213084(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid

Product 1

HCID 67021632HCID 67021632, compound

Procedure

The title compound is prepared as described in Example 28 but using 2-(4-imidazo[4,5-b]pyridine-3-yl-phenyl)-acetic acid and 5-cyclopropyl-2-phenyl-2H-pyrazol-3-ylamine. Title compound: ES-MS: 435.50 [M+H]+; tR=1.34 min (System 3).

Workup

  1. customThe title compound is prepared

Sources & evidence

ORD record
ord-bb7776b1e01e475db32b560a03c24cd6
Source dataset
uspto-grants-2011_10
Patent number
US08030311B2

Reaction notes

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